I must realize an illustration that will be plotted in a big size (400 cm x 250 cm), how can I make that without lost in definition ? If I make a file with width 11339 pixel and height 7087 pixel is a very big file and my computer work very slow.
Buy more memory. If you can, buy a larger computer.
A file that large is about 230 MB in RGB, or about 306 MB in CMYK. That’s not unreasonably large; I work with files that large or larger on a regular basis.
I have manipulated files well over 400 MB in size on a several-generations-old, 400MHz G3 system without difficulty. However, that system has 640 MB of RAM, and would be better off with more still. If you intend to work on files in the 200-400 MB range, it is absolutely essential that your computer have sufficient RAM–it’s the single best investment you can make in Photoshop speed.
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